Sign in →

Test Code GASTN Gastrin Immunostain, Technical Component Only


Shipping Instructions


Attach the green pathology address label and the pink Immunostains Technical Only label, included in the kit, to the outside of the transport container.



Specimen Required


Supplies: Immunostain Technical Only Envelope (T693)

Specimen Type: Tissue

Container/Tube: Immunostains Technical Only Envelope (T693)

Preferred: 2 unstained positively charged glass slide (25 x 75 x 1mm) per test ordered; sections 4-microns thick.

Acceptable: Formalin-fixed, paraffin-embedded (FFPE) tissue block

Additional Information:

1.  Information on accessing digital images of IHC stains and the manual requisition form can be accessed through this website: www.mayomedicallaboratories.com/test-info/ihc/index.html 

2. Clients ordering stains using a manual requisition form will not have access to digital images.

3. Clients wishing to access digital images must place the order for IHC stains electronically. Information regarding digital imaging can be accessed through this website: www.mayomedicallaboratories.com/test-info/ihc/faq.html 


Secondary ID

70439

Useful For

Aids in the characterization of islet cell tumors and endocrine tumors of the gastrointestinal tract

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
IHTOI IHC Initial, Tech Only No No
IHTOA IHC Additional, Tech Only No No

Method Name

Immunohistochemistry

Reporting Name

Gastrin IHC, Tech Only

Specimen Type

TECHONLY

Specimen Stability Information

Specimen Type Temperature Time
TECHONLY Ambient (preferred)
  Refrigerated 

Reject Due To

Hemolysis

NA

Lipemia

NA

Icterus

NA

Other

Wet/frozen tissue, Cytology smears, Nonformalin fixed tissue, Nonparaffin embedded tissue, Noncharged slides, ProbeOn slides

Clinical Information

Gastrin is a polypeptide hormone produced and secreted by G cells in the antral mucosa of the stomach and in the duodenum and upper jejunum. The hormone is a potent stimulant of acid secretion and also increases gastric motility. Gastrin staining can identify G cells in the antral stomach and help characterize some islet cell tumors and other neuroendocrine tumors.

Interpretation

This test includes only technical performance of the stain (no pathologist interpretation is performed). If diagnostic consultation by a pathologist is required order PATHC / Pathology Consultation.

 

The positive and negative controls are verified as showing appropriate immunoreactivity. If a control tissue is not included on the slide, a scanned image of the relevant quality control tissue is available upon request. Contact 855-516-8404.

 

Interpretation of this test should be performed in the context of the patient's clinical history and other diagnostic tests by a qualified pathologist.

Clinical Reference

1. Blumenfeld W, Chandhoke DK, Sagerman, T, Turi GK: Neuroendocrine differentiation in gastric adenocarcinomas. An immunohistochemical study. Archives of Pathology and Laboratory Medicine 1996;120(5):478-481

2. Kasacka I, Lebkowski W, Janiuk I, et al: Immunohistochemical identification and localisation of gastrin and somatostatin in endocrine cells of human pyloric gastric mucosa. Folia Morphol 71(1):39-44

3. Thomas RM, Baybick JH, Elsayed AM, Sobin LH: Gastric carcinoids an immunohistochemical and clinicopathologic study of 104 patients. Cancer 1994;73(8):2053-2058

Day(s) and Time(s) Performed

Monday through Friday

Analytic Time

1 day

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

88342-TC, primary

88341-TC, if additional IHC

LOINC Code Information

Result ID Test Result Name Result LOINC Value
70752 Gastrin IHC, Tech Only No LOINC Needed