Sign in →

Test Code LATI LAT Immunostain, Technical Component Only


Shipping Instructions


Attach the green pathology address label and the pink Immunostain Technical Only label included in the kit to the outside of the transport container.



Specimen Required


Supplies: Immunostain Technical Only Envelope (T693)

Specimen Type: Tissue

Container/Tube: Immunostain Technical Only Envelope (T693)

Preferred: 2 unstained positively charged glass slide (25- x 75- x 1-mm) per test ordered; sections 4-microns thick.

Acceptable: Formalin-fixed, paraffin-embedded (FFPE) tissue block

Additional Information:

1. Information on accessing digital images of IHC stains and the manual requisition form can be accessed through this website: www.mayomedicallaboratories.com/test-info/ihc/index.html

2. Clients ordering stains using a manual requisition form will not have access to digital images.

3. Clients wishing to access digital images must place the order for IHC stains electronically. Information regarding digital imaging can be accessed through this website: www.mayomedicallaboratories.com/test-info/ihc/faq.html


Secondary ID

70632

Method Name

Immunohistochemistry

Reporting Name

LAT IHC, Tech Only

Specimen Type

TECHONLY

Specimen Stability Information

Specimen Type Temperature Time
TECHONLY Ambient (preferred)
  Refrigerated 

Reject Due To

Hemolysis

NA

Lipemia

NA

Icterus

NA

Other

Wet/frozen tissue
Cytology smears
Nonformalin fixed tissue
Nonparaffin embedded tissue
Noncharged slides
Probe on slides

Clinical Information

Linker for activation of T cells (LAT) is a transmembrane protein that plays an important role in linking engagement of the T-cell receptor (TCR) to biochemical events of T-cell activation. LAT is expressed on most T cells but is not expressed on B cells, macrophages/monocytes, dendritic cells, or epithelial cells.

Interpretation

This test includes only technical performance of the stain (no pathologist interpretation is performed). If diagnostic consultation by a pathologist is required order PATHC / Pathology Consultation.

 

The positive and negative controls are verified as showing appropriate immunoreactivity. If a control tissue is not included on the slide, a scanned image of the relevant quality control tissue is available upon request. Contact 855-516-8404.

 

Interpretation of this test should be performed in the context of the patient's clinical history and other diagnostic tests by a qualified pathologist.

Clinical Reference

1. Ungari M, Pellegrini W, Borlenghi E, et al: LAT (linker for activation of T cells): a useful marker for megakaryocyte evaluation on bone marrow biopsies. Pathologica 2002 Dec;94(6):325-330

2. Facchetti F, Chan JK, Zhang W, et al: Linker for activation of T cells (LAT), a novel immunohistochemical marker for T cells, NK cells, mast cells and megakaryocytes: evaluation in normal and pathological conditions. Am J Pathol 1999 Apr;154(4):1037-1046

Day(s) and Time(s) Performed

Monday through Friday

Analytic Time

1 day

Performing Laboratory

Mayo Medical Laboratories in Rochester

LOINC Code Information

Result ID Test Result Name Result LOINC Value
70903 LAT IHC, Tech Only No LOINC Needed