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Test Code OLINR Oligosaccharide Screen, Random, Urine

Secondary ID

38001

Method Name

Only orderable as part of a profile, See LYSDU / Lysosomal Storage Disorders Screen, Urine.

 

For information regarding oligosaccharides, see OLIGU / Oligosaccharide Screen, Urine.

 

Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS)

Reporting Name

Oligosaccharide Screen, U

Specimen Type

Urine


Necessary Information


Patient's age is required.



Specimen Required


Only orderable as part of a profile. See LYSDU / Lysosomal Storage Disorders Screen, Urine.

 

For information regarding oligosaccharides, see OLIGU / Oligosaccharide Screen, Urine.

 

Supplies: Urine Tubes, 10 mL (T068)

Specimen Volume: 6 mL

Pediatric: 2 mL

Collection Instructions:

1. Collect a random urine specimen (early morning preferred).

2. Immediately freeze specimen.


Specimen Stability Information

Specimen Type Temperature Time
Urine Frozen (preferred) 365 days
  Refrigerated  15 days
  Ambient  7 days

Reference Values

Only orderable as part of a profile. See LYSDU / Lysosomal Storage Disorders Screen, Urine.

 

For information regarding oligosaccharides, see OLIGU / Oligosaccharide Screen, Urine.

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

84377

Useful For

Screening for possible oligosaccharidoses

Disease States

  • Sialidosis
  • Galactosialidosis

Specimen Minimum Volume

2 mL

Reject Due To

Hemolysis

NA

Lipemia

NA

Icterus

NA

Other

NA

Clinical Information

Oligosaccharidoses are characterized by the abnormal accumulation of incompletely degraded oligosaccharides in cells and tissues and the corresponding increase of related free oligosaccharides in the urine.

 

Clinical features of oligosaccharidoses often overlap; therefore, urine screening is an important tool in the initial workup for these disorders.

 

Enzyme or molecular analysis is required to make a definitive diagnosis.

Interpretation

This is a screening test; not all oligosaccharidoses are detected. The resulting excretion profile may be characteristic of a specific disorder; however, abnormal results require confirmation by enzyme assay or molecular genetic testing.

 

When abnormal results are detected with characteristic patterns, a detailed interpretation is given, including an overview of results and significance, a correlation to available clinical information, elements of differential diagnosis, recommendations for additional confirmatory studies (enzyme assay, molecular genetic analysis).

Analytic Time

14 days